Review



c1005 staining solution  (Beyotime)


Bioz Verified Symbol Beyotime is a verified supplier
Bioz Manufacturer Symbol Beyotime manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 99

    Structured Review

    Beyotime c1005 staining solution
    C1005 Staining Solution, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 2090 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/DAPI+Staining+Solution/pm42880593-220-13-19
    Average 99 stars, based on 2090 article reviews
    c1005 staining solution - by Bioz Stars, 2026-10
    99/100 stars

    Images

    Related Articles

    Staining:

    Article Title: TRPC6-TXNIP-NLRP3 signaling axis is involved in type 2 diabetes-associated cognitive dysfunction and the intervention of ginsenoside Rg1.
    Article Snippet: Type 2 diabetes-associated cognitive dysfunction (TDACD) poses a significant global public health challenge.. However, the core molecular mechanisms underlying its pathogenesis remain incompletely understood, and the development of effective therapeutic interventions continues to face considerable obstacles.. Here, we identify the role of the TRPC6-TXNIP-NLRP3 signaling axis in TDACD and to investigate the protective effects and mechanisms of ginsenoside Rg1 against TDACD.

    Article Title: TRPM7 function in ischemia-reperfusion renal injury and its regulatory mechanism of PARthanatos
    Article Snippet: .. Upon completion of all labeling procedures, DAPI staining solution (C1005, Beyotime, Shanghai, China) was added for 5 min of nuclear staining in the dark, and residual DAPI was washed off with PBS. .. Slides were treated with tissue autofluorescence quencher for 5 min in darkness and rinsed under running tap water for 10 min, then mounted with anti-fluorescence quenching mounting medium (P0126, Beyotime, Shanghai, China).

    Article Title: Establishment and validation of porcine embryo genomic selection system through SCNT technique.
    Article Snippet: After ten washes, embryos were placed into diluted secondary antibodies (anti-mouse IgG 488, Abbkine, A23210, 1:500; anti-rabbit IgG 549, Abbkine, A23320, 1:500) for 1 h at room temperature, followed by another ten washes. .. Finally, embryos were incubated in DAPI staining solution for 3 min and washed ten times before mounting in a 2-μL drop of mounting medium (Beyotime, P0126) on a glass slide. ..

    Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.
    Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells.

    Article Title: Osthole promotes cell senescence-like phenotype to enhance radiosensitivity in non-small cell lung carcinoma possibly through modulating the Sirt1/NF-κB pathway
    Article Snippet: Background Radioresistance is a major problem in non-small cell lung carcinoma (NSCLC) treatment.. Osthole is a natural coumarin with antitumor effects.. This research sought to clarify if Osthole enhances the sensitivity of NSCLC to radiotherapy and to uncover the underlying mechanisms involved.

    Article Title: Butyrate counteracts maternal obesity-induced cardiac defects by promoting PLEKHG3-actin binding
    Article Snippet: Vector TrueVIEW kit , Vector laboratories , SP-8400. .. DAPI Staining Solution , Beyotime , C1006. .. mTeSR1 medium , STEMCELL , 85850.

    Article Title: Polygonatum sibiricum polysaccharide alleviates type 2 diabetes-associated testicular dysfunction in mice in association with steroidogenesis-related and blood-testis barrier-associated changes
    Article Snippet: Antibodies against StAR (cat. 12225-1-AP) and Cyp11a1 (cat. 13363-1-AP) were obtained from Proteintech Group, Inc. (China). .. ZO-1 (cat. AF0321), Occludin (cat. AF7644), DAPI staining solution (cat. P0131), and SDS-PAGE gel preparation kit (cat. P0012AC) were purchased from Beyotime Biotechnology (China). .. BODIPY 493/ 503 (cat. D3922), BCA protein assay kit (cat. 23,225), and anti-rabbit IgG secondary antibody (cat. 31,460) were obtained from Thermo Fisher Scientific (USA).

    Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma
    Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance.

    Labeling:

    Article Title: TRPM7 function in ischemia-reperfusion renal injury and its regulatory mechanism of PARthanatos
    Article Snippet: .. Upon completion of all labeling procedures, DAPI staining solution (C1005, Beyotime, Shanghai, China) was added for 5 min of nuclear staining in the dark, and residual DAPI was washed off with PBS. .. Slides were treated with tissue autofluorescence quencher for 5 min in darkness and rinsed under running tap water for 10 min, then mounted with anti-fluorescence quenching mounting medium (P0126, Beyotime, Shanghai, China).

    Incubation:

    Article Title: Establishment and validation of porcine embryo genomic selection system through SCNT technique.
    Article Snippet: After ten washes, embryos were placed into diluted secondary antibodies (anti-mouse IgG 488, Abbkine, A23210, 1:500; anti-rabbit IgG 549, Abbkine, A23320, 1:500) for 1 h at room temperature, followed by another ten washes. .. Finally, embryos were incubated in DAPI staining solution for 3 min and washed ten times before mounting in a 2-μL drop of mounting medium (Beyotime, P0126) on a glass slide. ..

    Article Title: Osthole promotes cell senescence-like phenotype to enhance radiosensitivity in non-small cell lung carcinoma possibly through modulating the Sirt1/NF-κB pathway
    Article Snippet: Background Radioresistance is a major problem in non-small cell lung carcinoma (NSCLC) treatment.. Osthole is a natural coumarin with antitumor effects.. This research sought to clarify if Osthole enhances the sensitivity of NSCLC to radiotherapy and to uncover the underlying mechanisms involved.

    Glass:

    Article Title: Establishment and validation of porcine embryo genomic selection system through SCNT technique.
    Article Snippet: After ten washes, embryos were placed into diluted secondary antibodies (anti-mouse IgG 488, Abbkine, A23210, 1:500; anti-rabbit IgG 549, Abbkine, A23320, 1:500) for 1 h at room temperature, followed by another ten washes. .. Finally, embryos were incubated in DAPI staining solution for 3 min and washed ten times before mounting in a 2-μL drop of mounting medium (Beyotime, P0126) on a glass slide. ..

    Immunostaining:

    Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.
    Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells.

    Blocking Assay:

    Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.
    Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells.

    Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma
    Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance.

    BIA-KA:

    Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.
    Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells.

    Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma
    Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance.

    Protein Concentration:

    Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.
    Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells.

    Membrane:

    Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.
    Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells.

    TUNEL Assay:

    Article Title: Osthole promotes cell senescence-like phenotype to enhance radiosensitivity in non-small cell lung carcinoma possibly through modulating the Sirt1/NF-κB pathway
    Article Snippet: Background Radioresistance is a major problem in non-small cell lung carcinoma (NSCLC) treatment.. Osthole is a natural coumarin with antitumor effects.. This research sought to clarify if Osthole enhances the sensitivity of NSCLC to radiotherapy and to uncover the underlying mechanisms involved.

    SDS Page:

    Article Title: Polygonatum sibiricum polysaccharide alleviates type 2 diabetes-associated testicular dysfunction in mice in association with steroidogenesis-related and blood-testis barrier-associated changes
    Article Snippet: Antibodies against StAR (cat. 12225-1-AP) and Cyp11a1 (cat. 13363-1-AP) were obtained from Proteintech Group, Inc. (China). .. ZO-1 (cat. AF0321), Occludin (cat. AF7644), DAPI staining solution (cat. P0131), and SDS-PAGE gel preparation kit (cat. P0012AC) were purchased from Beyotime Biotechnology (China). .. BODIPY 493/ 503 (cat. D3922), BCA protein assay kit (cat. 23,225), and anti-rabbit IgG secondary antibody (cat. 31,460) were obtained from Thermo Fisher Scientific (USA).

    Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma
    Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance.

    Stripping:

    Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma
    Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance.



    Similar Products

    97
    Miltenyi Biotec dapi
    Dapi, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/DAPI+Staining+Solution/pm42855519-284-0-2
    Average 97 stars, based on 1 article reviews
    dapi - by Bioz Stars, 2026-10
    97/100 stars
      Buy from Supplier

    99
    Beyotime c1005 staining solution
    C1005 Staining Solution, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/DAPI+Staining+Solution/pm42880593-220-13-19
    Average 99 stars, based on 1 article reviews
    c1005 staining solution - by Bioz Stars, 2026-10
    99/100 stars
      Buy from Supplier

    96
    Boster Bio dapi staining solution
    LF-PVA@Pro NPs alleviate CRS-induced neuropathological damage and restore neuronal activity and neurotransmitter-related signaling in the VTA and NAc. ( A ) Representative H&E staining images of the ventral tegmental area and nucleus accumbens from the control, CRS, free-propofol, PVA@Pro NPs and LF-PVA@Pro NPs groups. Boxed regions are shown at higher magnification. ( B ) Quantification of histopathological injury scores in the VTA and NAc. ( C ) Representative Nissl-staining images of the VTA and NAc in the indicated groups, with enlarged views of the selected regions. ( D) Quantification of morphologically normal Nissl-positive neurons in the VTA and NAc. ( E ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the VTA. Nuclei were <t>counterstained</t> with <t>DAPI.</t> ( F ) Quantification of c-Fos and GABA fluorescence intensities in the VTA. ( G ) Quantification of c-Fos and DAT fluorescence intensities in the VTA. ( H ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the NAc. ( I ) Quantification of c-Fos and GABA fluorescence intensities in the NAc. ( J ) Quantification of c-Fos and DAT fluorescence intensities in the NAc. CRS exposure caused marked histopathological injury, loss of Nissl-positive neurons, and reductions in c-Fos-, GABA-, and DAT-associated fluorescence signals in the VTA and NAc. LF-PVA@Pro NPs treatment attenuated tissue injury and produced greater recovery of neuronal integrity and functional marker expression than free propofol. Data are presented as the mean ± SD (n=3). *p <0.05, p <0.01, ***p <0.001 , and ****p <0.0001 ; ns, not significant.
    Dapi Staining Solution, supplied by Boster Bio, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/DAPI+(4'%2C6-Diamidino-2-Phenylindole%2C+Dihydrochloride)+for+nucleic+acid+staining/pmc13678437-225-6-9
    Average 96 stars, based on 1 article reviews
    dapi staining solution - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    94
    Miltenyi Biotec dapi staining solution
    LF-PVA@Pro NPs alleviate CRS-induced neuropathological damage and restore neuronal activity and neurotransmitter-related signaling in the VTA and NAc. ( A ) Representative H&E staining images of the ventral tegmental area and nucleus accumbens from the control, CRS, free-propofol, PVA@Pro NPs and LF-PVA@Pro NPs groups. Boxed regions are shown at higher magnification. ( B ) Quantification of histopathological injury scores in the VTA and NAc. ( C ) Representative Nissl-staining images of the VTA and NAc in the indicated groups, with enlarged views of the selected regions. ( D) Quantification of morphologically normal Nissl-positive neurons in the VTA and NAc. ( E ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the VTA. Nuclei were <t>counterstained</t> with <t>DAPI.</t> ( F ) Quantification of c-Fos and GABA fluorescence intensities in the VTA. ( G ) Quantification of c-Fos and DAT fluorescence intensities in the VTA. ( H ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the NAc. ( I ) Quantification of c-Fos and GABA fluorescence intensities in the NAc. ( J ) Quantification of c-Fos and DAT fluorescence intensities in the NAc. CRS exposure caused marked histopathological injury, loss of Nissl-positive neurons, and reductions in c-Fos-, GABA-, and DAT-associated fluorescence signals in the VTA and NAc. LF-PVA@Pro NPs treatment attenuated tissue injury and produced greater recovery of neuronal integrity and functional marker expression than free propofol. Data are presented as the mean ± SD (n=3). *p <0.05, p <0.01, ***p <0.001 , and ****p <0.0001 ; ns, not significant.
    Dapi Staining Solution, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/MACSima+Stain+Support+Kit%2C+human/10__1038_slash_s42003___026___11109___8-243-16-19
    Average 94 stars, based on 1 article reviews
    dapi staining solution - by Bioz Stars, 2026-10
    94/100 stars
      Buy from Supplier

    99
    Beyotime 4 6 diamidino 2 phenylindole dapi staining solution
    LF-PVA@Pro NPs alleviate CRS-induced neuropathological damage and restore neuronal activity and neurotransmitter-related signaling in the VTA and NAc. ( A ) Representative H&E staining images of the ventral tegmental area and nucleus accumbens from the control, CRS, free-propofol, PVA@Pro NPs and LF-PVA@Pro NPs groups. Boxed regions are shown at higher magnification. ( B ) Quantification of histopathological injury scores in the VTA and NAc. ( C ) Representative Nissl-staining images of the VTA and NAc in the indicated groups, with enlarged views of the selected regions. ( D) Quantification of morphologically normal Nissl-positive neurons in the VTA and NAc. ( E ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the VTA. Nuclei were <t>counterstained</t> with <t>DAPI.</t> ( F ) Quantification of c-Fos and GABA fluorescence intensities in the VTA. ( G ) Quantification of c-Fos and DAT fluorescence intensities in the VTA. ( H ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the NAc. ( I ) Quantification of c-Fos and GABA fluorescence intensities in the NAc. ( J ) Quantification of c-Fos and DAT fluorescence intensities in the NAc. CRS exposure caused marked histopathological injury, loss of Nissl-positive neurons, and reductions in c-Fos-, GABA-, and DAT-associated fluorescence signals in the VTA and NAc. LF-PVA@Pro NPs treatment attenuated tissue injury and produced greater recovery of neuronal integrity and functional marker expression than free propofol. Data are presented as the mean ± SD (n=3). *p <0.05, p <0.01, ***p <0.001 , and ****p <0.0001 ; ns, not significant.
    4 6 Diamidino 2 Phenylindole Dapi Staining Solution, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/DAPI+Staining+Solution/pm42844620-90-10-14
    Average 99 stars, based on 1 article reviews
    4 6 diamidino 2 phenylindole dapi staining solution - by Bioz Stars, 2026-10
    99/100 stars
      Buy from Supplier

    99
    Beyotime dapi staining solution
    LF-PVA@Pro NPs alleviate CRS-induced neuropathological damage and restore neuronal activity and neurotransmitter-related signaling in the VTA and NAc. ( A ) Representative H&E staining images of the ventral tegmental area and nucleus accumbens from the control, CRS, free-propofol, PVA@Pro NPs and LF-PVA@Pro NPs groups. Boxed regions are shown at higher magnification. ( B ) Quantification of histopathological injury scores in the VTA and NAc. ( C ) Representative Nissl-staining images of the VTA and NAc in the indicated groups, with enlarged views of the selected regions. ( D) Quantification of morphologically normal Nissl-positive neurons in the VTA and NAc. ( E ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the VTA. Nuclei were <t>counterstained</t> with <t>DAPI.</t> ( F ) Quantification of c-Fos and GABA fluorescence intensities in the VTA. ( G ) Quantification of c-Fos and DAT fluorescence intensities in the VTA. ( H ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the NAc. ( I ) Quantification of c-Fos and GABA fluorescence intensities in the NAc. ( J ) Quantification of c-Fos and DAT fluorescence intensities in the NAc. CRS exposure caused marked histopathological injury, loss of Nissl-positive neurons, and reductions in c-Fos-, GABA-, and DAT-associated fluorescence signals in the VTA and NAc. LF-PVA@Pro NPs treatment attenuated tissue injury and produced greater recovery of neuronal integrity and functional marker expression than free propofol. Data are presented as the mean ± SD (n=3). *p <0.05, p <0.01, ***p <0.001 , and ****p <0.0001 ; ns, not significant.
    Dapi Staining Solution, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/DAPI+Staining+Solution/pm42844620-95-5-24
    Average 99 stars, based on 1 article reviews
    dapi staining solution - by Bioz Stars, 2026-10
    99/100 stars
      Buy from Supplier

    99
    Beyotime 6 diamidino 2 phenylindole dapi staining solution
    LF-PVA@Pro NPs alleviate CRS-induced neuropathological damage and restore neuronal activity and neurotransmitter-related signaling in the VTA and NAc. ( A ) Representative H&E staining images of the ventral tegmental area and nucleus accumbens from the control, CRS, free-propofol, PVA@Pro NPs and LF-PVA@Pro NPs groups. Boxed regions are shown at higher magnification. ( B ) Quantification of histopathological injury scores in the VTA and NAc. ( C ) Representative Nissl-staining images of the VTA and NAc in the indicated groups, with enlarged views of the selected regions. ( D) Quantification of morphologically normal Nissl-positive neurons in the VTA and NAc. ( E ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the VTA. Nuclei were <t>counterstained</t> with <t>DAPI.</t> ( F ) Quantification of c-Fos and GABA fluorescence intensities in the VTA. ( G ) Quantification of c-Fos and DAT fluorescence intensities in the VTA. ( H ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the NAc. ( I ) Quantification of c-Fos and GABA fluorescence intensities in the NAc. ( J ) Quantification of c-Fos and DAT fluorescence intensities in the NAc. CRS exposure caused marked histopathological injury, loss of Nissl-positive neurons, and reductions in c-Fos-, GABA-, and DAT-associated fluorescence signals in the VTA and NAc. LF-PVA@Pro NPs treatment attenuated tissue injury and produced greater recovery of neuronal integrity and functional marker expression than free propofol. Data are presented as the mean ± SD (n=3). *p <0.05, p <0.01, ***p <0.001 , and ****p <0.0001 ; ns, not significant.
    6 Diamidino 2 Phenylindole Dapi Staining Solution, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/DAPI+Staining+Solution/pm42834580-130-20-25
    Average 99 stars, based on 1 article reviews
    6 diamidino 2 phenylindole dapi staining solution - by Bioz Stars, 2026-10
    99/100 stars
      Buy from Supplier

    99
    Beyotime p0096 dapi staining solution
    LF-PVA@Pro NPs alleviate CRS-induced neuropathological damage and restore neuronal activity and neurotransmitter-related signaling in the VTA and NAc. ( A ) Representative H&E staining images of the ventral tegmental area and nucleus accumbens from the control, CRS, free-propofol, PVA@Pro NPs and LF-PVA@Pro NPs groups. Boxed regions are shown at higher magnification. ( B ) Quantification of histopathological injury scores in the VTA and NAc. ( C ) Representative Nissl-staining images of the VTA and NAc in the indicated groups, with enlarged views of the selected regions. ( D) Quantification of morphologically normal Nissl-positive neurons in the VTA and NAc. ( E ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the VTA. Nuclei were <t>counterstained</t> with <t>DAPI.</t> ( F ) Quantification of c-Fos and GABA fluorescence intensities in the VTA. ( G ) Quantification of c-Fos and DAT fluorescence intensities in the VTA. ( H ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the NAc. ( I ) Quantification of c-Fos and GABA fluorescence intensities in the NAc. ( J ) Quantification of c-Fos and DAT fluorescence intensities in the NAc. CRS exposure caused marked histopathological injury, loss of Nissl-positive neurons, and reductions in c-Fos-, GABA-, and DAT-associated fluorescence signals in the VTA and NAc. LF-PVA@Pro NPs treatment attenuated tissue injury and produced greater recovery of neuronal integrity and functional marker expression than free propofol. Data are presented as the mean ± SD (n=3). *p <0.05, p <0.01, ***p <0.001 , and ****p <0.0001 ; ns, not significant.
    P0096 Dapi Staining Solution, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dapi+staining+solution/DAPI+Staining+Solution/pm42826097-286-134-138
    Average 99 stars, based on 1 article reviews
    p0096 dapi staining solution - by Bioz Stars, 2026-10
    99/100 stars
      Buy from Supplier

    Image Search Results


    LF-PVA@Pro NPs alleviate CRS-induced neuropathological damage and restore neuronal activity and neurotransmitter-related signaling in the VTA and NAc. ( A ) Representative H&E staining images of the ventral tegmental area and nucleus accumbens from the control, CRS, free-propofol, PVA@Pro NPs and LF-PVA@Pro NPs groups. Boxed regions are shown at higher magnification. ( B ) Quantification of histopathological injury scores in the VTA and NAc. ( C ) Representative Nissl-staining images of the VTA and NAc in the indicated groups, with enlarged views of the selected regions. ( D) Quantification of morphologically normal Nissl-positive neurons in the VTA and NAc. ( E ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the VTA. Nuclei were counterstained with DAPI. ( F ) Quantification of c-Fos and GABA fluorescence intensities in the VTA. ( G ) Quantification of c-Fos and DAT fluorescence intensities in the VTA. ( H ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the NAc. ( I ) Quantification of c-Fos and GABA fluorescence intensities in the NAc. ( J ) Quantification of c-Fos and DAT fluorescence intensities in the NAc. CRS exposure caused marked histopathological injury, loss of Nissl-positive neurons, and reductions in c-Fos-, GABA-, and DAT-associated fluorescence signals in the VTA and NAc. LF-PVA@Pro NPs treatment attenuated tissue injury and produced greater recovery of neuronal integrity and functional marker expression than free propofol. Data are presented as the mean ± SD (n=3). *p <0.05, p <0.01, ***p <0.001 , and ****p <0.0001 ; ns, not significant.

    Journal: International Journal of Nanomedicine

    Article Title: Lactoferrin-Modified Ultra-Sustained Release Propofol Nanoparticles for Multi-Pathway Therapy of Depression via Intraperitoneal Injection

    doi: 10.2147/IJN.S645818

    Figure Lengend Snippet: LF-PVA@Pro NPs alleviate CRS-induced neuropathological damage and restore neuronal activity and neurotransmitter-related signaling in the VTA and NAc. ( A ) Representative H&E staining images of the ventral tegmental area and nucleus accumbens from the control, CRS, free-propofol, PVA@Pro NPs and LF-PVA@Pro NPs groups. Boxed regions are shown at higher magnification. ( B ) Quantification of histopathological injury scores in the VTA and NAc. ( C ) Representative Nissl-staining images of the VTA and NAc in the indicated groups, with enlarged views of the selected regions. ( D) Quantification of morphologically normal Nissl-positive neurons in the VTA and NAc. ( E ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the VTA. Nuclei were counterstained with DAPI. ( F ) Quantification of c-Fos and GABA fluorescence intensities in the VTA. ( G ) Quantification of c-Fos and DAT fluorescence intensities in the VTA. ( H ) Representative immunofluorescence images of c-Fos&GABA and c-Fos&DAT staining in the NAc. ( I ) Quantification of c-Fos and GABA fluorescence intensities in the NAc. ( J ) Quantification of c-Fos and DAT fluorescence intensities in the NAc. CRS exposure caused marked histopathological injury, loss of Nissl-positive neurons, and reductions in c-Fos-, GABA-, and DAT-associated fluorescence signals in the VTA and NAc. LF-PVA@Pro NPs treatment attenuated tissue injury and produced greater recovery of neuronal integrity and functional marker expression than free propofol. Data are presented as the mean ± SD (n=3). *p <0.05, p <0.01, ***p <0.001 , and ****p <0.0001 ; ns, not significant.

    Article Snippet: The sections were subsequently counterstained with DAPI staining solution (Boster Biological Technology Co., Ltd.) for 15 min.

    Techniques: Activity Assay, Staining, Control, Immunofluorescence, Fluorescence, Tissue, Produced, Functional Assay, Marker, Expressing