c1005 staining solution (Beyotime)
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C1005 Staining Solution, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 2090 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapi+staining+solution/DAPI+Staining+Solution/pm42880593-220-13-19
Average 99 stars, based on 2090 article reviews
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Staining:Article Title: TRPC6-TXNIP-NLRP3 signaling axis is involved in type 2 diabetes-associated cognitive dysfunction and the intervention of ginsenoside Rg1. Article Snippet: Type 2 diabetes-associated cognitive dysfunction (TDACD) poses a significant global public health challenge.. However, the core molecular mechanisms underlying its pathogenesis remain incompletely understood, and the development of effective therapeutic interventions continues to face considerable obstacles.. Here, we identify the role of the TRPC6-TXNIP-NLRP3 signaling axis in TDACD and to investigate the protective effects and mechanisms of ginsenoside Rg1 against TDACD. Article Title: TRPM7 function in ischemia-reperfusion renal injury and its regulatory mechanism of PARthanatos Article Snippet: .. Upon completion of all labeling procedures, Article Title: Establishment and validation of porcine embryo genomic selection system through SCNT technique. Article Snippet: After ten washes, embryos were placed into diluted secondary antibodies (anti-mouse IgG 488, Abbkine, A23210, 1:500; anti-rabbit IgG 549, Abbkine, A23320, 1:500) for 1 h at room temperature, followed by another ten washes. .. Finally, embryos were incubated in Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity. Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells. Article Title: Osthole promotes cell senescence-like phenotype to enhance radiosensitivity in non-small cell lung carcinoma possibly through modulating the Sirt1/NF-κB pathway Article Snippet: Background Radioresistance is a major problem in non-small cell lung carcinoma (NSCLC) treatment.. Osthole is a natural coumarin with antitumor effects.. This research sought to clarify if Osthole enhances the sensitivity of NSCLC to radiotherapy and to uncover the underlying mechanisms involved. Article Title: Butyrate counteracts maternal obesity-induced cardiac defects by promoting PLEKHG3-actin binding Article Snippet: Vector TrueVIEW kit , Vector laboratories , SP-8400. .. Article Title: Polygonatum sibiricum polysaccharide alleviates type 2 diabetes-associated testicular dysfunction in mice in association with steroidogenesis-related and blood-testis barrier-associated changes Article Snippet: Antibodies against StAR (cat. 12225-1-AP) and Cyp11a1 (cat. 13363-1-AP) were obtained from Proteintech Group, Inc. (China). .. ZO-1 (cat. AF0321), Occludin (cat. AF7644), Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance. Labeling:Article Title: TRPM7 function in ischemia-reperfusion renal injury and its regulatory mechanism of PARthanatos Article Snippet: .. Upon completion of all labeling procedures, Incubation:Article Title: Establishment and validation of porcine embryo genomic selection system through SCNT technique. Article Snippet: After ten washes, embryos were placed into diluted secondary antibodies (anti-mouse IgG 488, Abbkine, A23210, 1:500; anti-rabbit IgG 549, Abbkine, A23320, 1:500) for 1 h at room temperature, followed by another ten washes. .. Finally, embryos were incubated in Article Title: Osthole promotes cell senescence-like phenotype to enhance radiosensitivity in non-small cell lung carcinoma possibly through modulating the Sirt1/NF-κB pathway Article Snippet: Background Radioresistance is a major problem in non-small cell lung carcinoma (NSCLC) treatment.. Osthole is a natural coumarin with antitumor effects.. This research sought to clarify if Osthole enhances the sensitivity of NSCLC to radiotherapy and to uncover the underlying mechanisms involved. Glass:Article Title: Establishment and validation of porcine embryo genomic selection system through SCNT technique. Article Snippet: After ten washes, embryos were placed into diluted secondary antibodies (anti-mouse IgG 488, Abbkine, A23210, 1:500; anti-rabbit IgG 549, Abbkine, A23320, 1:500) for 1 h at room temperature, followed by another ten washes. .. Finally, embryos were incubated in Immunostaining:Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity. Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells. Blocking Assay:Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity. Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells. Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance. BIA-KA:Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity. Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells. Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance. Protein Concentration:Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity. Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells. Membrane:Article Title: Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity. Article Snippet: Sarcopenic obesity (SO), characterized by concurrent muscle loss and excessive adiposity, lacks effective interventions.. This study investigated the enhanced effects of the selenomethionine (Se-Met) and magnolol (Mag) combination against SO using an integrated computational-experimental approach.. Network pharmacology and molecular docking predicted peroxisome proliferator-activated receptor γ (PPARγ) and the nuclear factor erythroid 2-related factor 2 glutathione peroxidase 4 (Nrf2 GPX4) axis as core targets, which was corroborated by single-cell transcriptomic data analysis showing their co-expression in muscle progenitor cells. TUNEL Assay:Article Title: Osthole promotes cell senescence-like phenotype to enhance radiosensitivity in non-small cell lung carcinoma possibly through modulating the Sirt1/NF-κB pathway Article Snippet: Background Radioresistance is a major problem in non-small cell lung carcinoma (NSCLC) treatment.. Osthole is a natural coumarin with antitumor effects.. This research sought to clarify if Osthole enhances the sensitivity of NSCLC to radiotherapy and to uncover the underlying mechanisms involved. SDS Page:Article Title: Polygonatum sibiricum polysaccharide alleviates type 2 diabetes-associated testicular dysfunction in mice in association with steroidogenesis-related and blood-testis barrier-associated changes Article Snippet: Antibodies against StAR (cat. 12225-1-AP) and Cyp11a1 (cat. 13363-1-AP) were obtained from Proteintech Group, Inc. (China). .. ZO-1 (cat. AF0321), Occludin (cat. AF7644), Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance. Stripping:Article Title: Dual-targeting ferritin nanocages potentiate betulinic acid therapy against metastatic melanoma Article Snippet: Malignant melanoma is among the most aggressive and treatment-refractory skin malignancies, characterized by rapid metastatic progression, pronounced molecular heterogeneity, and frequent therapeutic resistance, all of which severely limit current treatment efficacy.. Betulinic acid (BA), a naturally derived pentacyclic triterpenoid, has emerged as a promising anti-melanoma agent owing to its intrinsic tumor-selective cytotoxicity and potent induction of mitochondrial apoptosis.. However, its clinical translation is markedly constrained by poor aqueous solubility, limited tumor selectivity in vivo, and rapid systemic clearance. |
